Subcategory
Other indications (e.g. myeloproliferative diseases), Non-Hodgkin lymphoma
Trial Type
First-Line-Therapy (Metastatic Disease/Hematology)
Description for experts
To demonstrate the superiority of de-escalated induction therapy followed by autologous stem cell transplantation compared to the standard MATRix protocol in terms of event-free survival (EFS).
Description for laymen
To demonstrate the superiority of de-escalated induction therapy followed by autologous stem cell transplantation compared to the standard MATRix protocol in terms of event-free survival (EFS).
JSON Data
{
"short_title": "OptiMATe",
"data_mode": "910",
"data_mode_number": "000000009",
"official_title": null,
"accrual_state": "running",
"therapeutic_value": "not_applicable",
"therapieansatz_value": "not_applicable",
"therapieintervention_value": "not_applicable",
"therapielinie_value": "first",
"ctgov_number": null,
"eudract_number": "2024-514473-21-00",
"general_contact_email": "sal-aml-register@ukdd.de",
"general_contact_phone": "+49 351-45818380",
"hauptpruefer_dd_name": null,
"description_laie_de": "Nachweis der \u00dcberlegenheit einer de-eskalierten Induktionstherapie gefolgt von autologer Stammzelltransplantation im Vergleich zum Standard MATRix-Protokoll in Bezug auf das Ereignisfreie \u00dcberleben (EFS).",
"description_laie_en": "To demonstrate the superiority of de-escalated induction therapy followed by autologous stem cell transplantation compared to the standard MATRix protocol in terms of event-free survival (EFS).",
"description_expert_de": "Nachweis der \u00dcberlegenheit einer de-eskalierten Induktionstherapie gefolgt von autologer Stammzelltransplantation im Vergleich zum Standard MATRix-Protokoll in Bezug auf das Ereignisfreie \u00dcberleben (EFS).",
"description_expert_en": "To demonstrate the superiority of de-escalated induction therapy followed by autologous stem cell transplantation compared to the standard MATRix protocol in terms of event-free survival (EFS).",
"rechtsgrundlage_value": null,
"phase_amg_value": null,
"main_cat_id": 4,
"sub_cat_id": 24
}
