Description for experts
This study is being done to find out if ZW171 is safe and can treat participants withadvanced (locally advanced [inoperable] and/or metastatic) mesothelin-expressing cancers.
Description for laymen
This study is being conducted to find out if ZW171 is safe and can treat participants with advanced (locally advanced [inoperable] and/or metastatic) mesothelin-expressing cancers.
JSON Data
{
"short_title": "Zymeworks ZWI-ZW171-101",
"data_mode": "900",
"data_mode_number": "000002385",
"official_title": "A Phase 1, Open-label, Multicenter Study of ZW171 in Participants With Advanced or Metastatic Ovarian Cancer, Non-small Cell Lung Cancer (NSCLC), and Other Mesothelin Expressing Cancers",
"accrual_state": "running",
"therapeutic_value": "therapeutic",
"therapieansatz_value": "palliativ",
"therapieintervention_value": "not_applicable",
"therapielinie_value": "not_applicable",
"ctgov_number": "NCT06523803",
"eudract_number": "2024-511119-11",
"general_contact_email": "ectu@ukdd.de",
"general_contact_phone": "+49 351-4587566",
"hauptpruefer_dd_name": "Prof. Dr. med. habil Martin Wermke",
"description_laie_de": "Diese Studie wird durchgef\u00fchrt, um herauszufinden, ob ZW171 sicher ist und Teilnehmer mit fortgeschrittenen (lokal fortgeschrittenen [inoperablen] und/oder metastasierten) Mesothelin-exprimierenden Krebsarten behandeln kann.",
"description_laie_en": "This study is being conducted to find out if ZW171 is safe and can treat participants with advanced (locally advanced [inoperable] and/or metastatic) mesothelin-expressing cancers.",
"description_expert_de": "Diese Studie wird durchgef\u00fchrt, um herauszufinden, ob ZW171 sicher ist und Teilnehmer mit fortgeschrittenen (lokal fortgeschrittenen [inoperablen] und/oder metastasierten) Mesothelin-exprimierenden Krebsarten behandeln kann.",
"description_expert_en": "This study is being done to find out if ZW171 is safe and can treat participants withadvanced (locally advanced [inoperable] and/or metastatic) mesothelin-expressing cancers.",
"rechtsgrundlage_value": "AMG",
"phase_amg_value": "I",
"main_cat_id": 10,
"sub_cat_id": 50
}