Zymeworks ZWI-ZW171-101

Section NCT
Category Thoracic tumors
Subcategory Non-small cell lung cancer (NSCLC)
Trial Type other systemic therapies
Description for experts This study is being done to find out if ZW171 is safe and can treat participants withadvanced (locally advanced [inoperable] and/or metastatic) mesothelin-expressing cancers.
Description for laymen This study is being conducted to find out if ZW171 is safe and can treat participants with advanced (locally advanced [inoperable] and/or metastatic) mesothelin-expressing cancers.
JSON Data { "short_title": "Zymeworks ZWI-ZW171-101", "data_mode": "900", "data_mode_number": "000002385", "official_title": "A Phase 1, Open-label, Multicenter Study of ZW171 in Participants With Advanced or Metastatic Ovarian Cancer, Non-small Cell Lung Cancer (NSCLC), and Other Mesothelin Expressing Cancers", "accrual_state": "running", "therapeutic_value": "therapeutic", "therapieansatz_value": "palliativ", "therapieintervention_value": "not_applicable", "therapielinie_value": "not_applicable", "ctgov_number": "NCT06523803", "eudract_number": "2024-511119-11", "general_contact_email": "ectu@ukdd.de", "general_contact_phone": "+49 351-4587566", "hauptpruefer_dd_name": "Prof. Dr. med. habil Martin Wermke", "description_laie_de": "Diese Studie wird durchgef\u00fchrt, um herauszufinden, ob ZW171 sicher ist und Teilnehmer mit fortgeschrittenen (lokal fortgeschrittenen [inoperablen] und/oder metastasierten) Mesothelin-exprimierenden Krebsarten behandeln kann.", "description_laie_en": "This study is being conducted to find out if ZW171 is safe and can treat participants with advanced (locally advanced [inoperable] and/or metastatic) mesothelin-expressing cancers.", "description_expert_de": "Diese Studie wird durchgef\u00fchrt, um herauszufinden, ob ZW171 sicher ist und Teilnehmer mit fortgeschrittenen (lokal fortgeschrittenen [inoperablen] und/oder metastasierten) Mesothelin-exprimierenden Krebsarten behandeln kann.", "description_expert_en": "This study is being done to find out if ZW171 is safe and can treat participants withadvanced (locally advanced [inoperable] and/or metastatic) mesothelin-expressing cancers.", "rechtsgrundlage_value": "AMG", "phase_amg_value": "I", "main_cat_id": 10, "sub_cat_id": 50 }
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Short name 900-000002385