BENITA

Ovarian cancer is the second most common gynecological cancer in women and is associated with the highest mortality. Older women are usually affected, and because of the non-specific symptoms, the disease is often only recognized late. Patients often suffer from the consequences of peritoneal metastases such as water retention in the abdomen and involvement of the digestive tract. Characteristic side effects of the disease and therapy are muscle loss and malnutrition. If these are not treated, they can become chronic. This increases the risk of further symptoms such as pain, depression or fatigue. Maintaining physical abilities and improving nutritional status could help survivors continue to lead self-determined, high-quality lives. In addition, the tolerability of the therapy and subsequent recovery could be improved.

{ "short_title": "BENITA", "data_mode": "900", "data_mode_number": "000002362", "official_title": "Bewegungs- und Ernaehrungsintervention bei Ovarialkarzinomen und die Entwicklung eines Versorgungskonzepts und Evaluation in der klinischen Routine.", "accrual_state": "running", "therapeutic_value": "therapeutic", "therapieansatz_value": "palliativ", "therapieintervention_value": "adjuvant", "therapielinie_value": "second", "ctgov_number": null, "eudract_number": null, "general_contact_email": "studiensekretariat.gyn@ukdd.de", "general_contact_phone": "+49 351-4584202", "hauptpruefer_dd_name": "Prof. Dr. med. Pauline Wimberger", "description_laie_de": "Eierstockkrebs ist die zweith\u00e4ufigste gyn\u00e4kologische Krebserkrankung bei Frauen und mit der h\u00f6chsten Sterblichkeit verbunden. Meist sind \u00e4ltere Frauen betroffen, und wegen der unspezifischen Symptome wird die Erkrankung oft erst sp\u00e4t erkannt. Die Patientinnen leiden h\u00e4ufig unter den Folgen von Bauchfellmetastasen wie Wassereinlagerungen im Bauchraum und dem Befall des Verdauungstraktes. Charakteristische Nebenwirkungen von Krankheit und Therapie sind Muskelschwund und Mangelern\u00e4hrung. Werden diese nicht behandelt, k\u00f6nnen sie chronisch werden. Dies erh\u00f6ht das Risiko weiterer Symptome wie Schmerz, Depression oder Fatigue. Die Aufrechterhaltung der k\u00f6rperlichen F\u00e4higkeiten und die Verbesserung des Ern\u00e4hrungszustandes k\u00f6nnten den \u00dcberlebenden helfen, auch weiterhin ein selbstbestimmtes Leben mit hoher Qualit\u00e4t zu f\u00fchren. Zudem k\u00f6nnten die Vertr\u00e4glichkeit der Therapie und die anschlie\u00dfende Erholung verbessert werden.", "description_laie_en": "Ovarian cancer is the second most common gynecological cancer in women and is associated with the highest mortality. Older women are usually affected, and because of the non-specific symptoms, the disease is often only recognized late. Patients often suffer from the consequences of peritoneal metastases such as water retention in the abdomen and involvement of the digestive tract. Characteristic side effects of the disease and therapy are muscle loss and malnutrition. If these are not treated, they can become chronic. This increases the risk of further symptoms such as pain, depression or fatigue. Maintaining physical abilities and improving nutritional status could help survivors continue to lead self-determined, high-quality lives. In addition, the tolerability of the therapy and subsequent recovery could be improved.", "description_expert_de": "Bewegungs- und Ern\u00e4hrungsintervention bei Ovarialkarzinom \u2013 Entwicklung eines Versorgungskonzepts und Evaluation in der klinischen Routine (BENITA)", "description_expert_en": "Exercise and nutrition intervention in ovarian cancer \u2013 development of a care concept and evaluation in clinical routine (BENITA)", "rechtsgrundlage_value": "BO", "phase_amg_value": null, "main_cat_id": 3, "sub_cat_id": 15 }